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Article

I222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) viruses.

PloS one - 1 Jan 2013

McKimm-Breschkin Jennifer L, Barrett Susan, Pudjiatmoko, Azhar Muhammad, Wong Frank Y K, Selleck Paul, Mohr Peter G, McGrane James, Kim Mia

Abstract excerpt

We have tested the susceptibility to neuraminidase inhibitors of 155 clade 2.1 H5N1 viruses from Indonesia, isolated between 2006-2008 as well as 12 clade 1 isolates from Thailand and Cambodia from 2004-2007 using a fluorometric MUNANA-based enzyme inhibition assay. The Thailand and Cambodian clade 1 isolates tested here were all susceptible to oseltamivir and zanamivir, and sequence comparison indicated that...

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Identifiers

PMID: 23776615
DOI: 10.1371/journal.pone.0066105
PMCID: PMC3679007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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