Article
Assays for monitoring susceptibility of influenza viruses to neuraminidase inhibitors.
Influenza and other respiratory viruses - 1 Jan 2013
Okomo-Adhiambo Margaret, Sheu Tiffany G, Gubareva Larisa V
Abstract excerpt
Close monitoring of drug susceptibility among human influenza viruses was necessitated by widespread resistance to M2 inhibitors in influenza H1N1 (pre-pandemic and 2009 pandemic) and H3N2 viruses, and of oseltamivir resistance in pre-pandemic H1N1 viruses. The FDA-approved neuraminidase (NA) inhibitors (NAIs), oseltamivir and zanamivir, as well as investigational NAIs, peramivir and laninamivir, are currently...
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