Article
Human hair melanins: what we have learned and have not learned from mouse coat color pigmentation.
Pigment cell & melanoma research - 1 Feb 2011
Ito Shosuke, Wakamatsu Kazumasa
Abstract excerpt
Hair pigmentation is one of the most conspicuous phenotypes in humans. Melanocytes produce two distinct types of melanin pigment: brown to black, indolic eumelanin and yellow to reddish brown, sulfur-containing pheomelanin. Biochemically, the precursor tyrosine and the key enzyme tyrosinase and the tyrosinase-related proteins are involved in eumelanogenesis, while only the additional presence of cysteine is...
Topics
- Animals
- Hair
- Humans
- Melanins
- Mice
- Models, Biological
- Mutation
- Skin Pigmentation
