Article
Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms.
Blood - 8 Aug 2013
Przychodzen Bartlomiej, Jerez Andres, Guinta Kathryn, Sekeres Mikkael A, Padgett Richard, Maciejewski Jaroslaw P, Makishima Hideki
Abstract excerpt
Recently, recurrent mutations of spliceosomal genes were frequently identified in myeloid malignancies, as well as other types of cancers. One of these spliceosomal genes, U2AF1, was affected by canonical somatic mutations in aggressive type of myeloid malignancies. We hypothesized that U2AF1 mut...
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