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Article

Could yeast prion domains originate from polyQ/N tracts?

Prion - 1 Jan 2000

Alexandrov Alexander I, Ter-Avanesyan Michael D

Abstract excerpt

A significant body of evidence shows that polyglutamine (polyQ) tracts are important for various biological functions. The characteristic polymorphism of polyQ length is thought to play an important role in the adaptation of organisms to their environment. However, proteins with expanded polyQ are prone to form amyloids, which cause diseases in humans and animals and toxicity in yeast. Saccharomyces cerevisiae...

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Identifiers

PMID: 23764835
DOI: 10.4161/pri.24628
PMCID: PMC3783105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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