Article
Association between the poly(ADP-ribose) polymerase-1 gene polymorphism and advanced pelvic organ prolapse.
Menopause (New York, N.Y.) - 1 Feb 2014
Kim Ji Young, Kim Eun Jae, Jeon Myung Jae, Kim Hoon, Moon Yeo Jung, Bai Sang Wook
Abstract excerpt
OBJECTIVE: Apoptotic cell death, probably induced by oxidative stress, contributes to the development of pelvic organ prolapse. Because poly(ADP-ribose) polymerase-1 is an important mediator of cellular response to oxidative stress, genetic variations in the poly(ADP-ribose) polymerase-1 gene may...
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