Association between susceptibility to advanced pelvic organ prolapse and glutathione S-transferase P1 Ile105Val polymorphism.

doi:10.1016/j.ejogrb.2014.01.028

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Article

Association between susceptibility to advanced pelvic organ prolapse and glutathione S-transferase P1 Ile105Val polymorphism.

European journal of obstetrics, gynecology, and reproductive biology - 1 Apr 2014

Kim Ji Young, Kim Eun Jae, Jeon Myung Jae, Kim Ran, Lee Min Woo, Kim Suhng Wook

Abstract excerpt

OBJECTIVE: Oxidative stress is associated with the pathogenesis of pelvic organ prolapse (POP). Because glutathione S-transferases (GSTs) are the major detoxification enzymes which protect cells against oxidative stress, genetic variations in the GST gene may modulate the risk of POP. This study aimed to determine the association between advanced POP and the polymorphisms of GSTM1, GSTT1 and GSTP1 (rs1695). STUDY...

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Identifiers

PMID: 24582550
DOI: 10.1016/j.ejogrb.2014.01.028

Genes

GSTP1
GSTM1
GSTT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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