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Article

RXRγ gene variants are associated with HIV lipodystrophy.

Pharmacogenetics and genomics - 1 Aug 2013

Pushpakom Sudeep P, Owen Andrew, Back David J, Pirmohamed Munir

Abstract excerpt

HIV lipodystrophy (HIVLD), associated with combination antiretroviral therapy (cART), leads to metabolic and cardiovascular diseases. Nuclear receptors play a central role in lipid homoeostasis and drug disposition; their genetic variants may predispose an individual to the development of HIVLD. DNA samples obtained from cART-treated HIV-positive patients with (HIVLD+; 124) and without (HIVLD-; 56) HIVLD were...

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Identifiers

PMID: 23759678
DOI: 10.1097/FPC.0b013e328362cfc6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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