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Article

Absence of TREM2 polymorphisms in patients with Alzheimer's disease and Frontotemporal Lobar Degeneration.

Neuroscience letters - 10 Jan 2007

Fenoglio Chiara, Galimberti Daniela, Piccio Laura, Scalabrini Diego, Panina Paola, Buonsanti Cecilia, Venturelli Eliana, Lovati Carlo, Forloni Gianluigi, Mariani Claudio, Bresolin Nereo, Scarpini Elio

Abstract excerpt

Triggering Receptor Expressed on Myeloid cells (TREM)2 deficiency originates a genetic syndrome characterized by bone cysts and presenile dementia, named Nasu-Hakola disease (NHD). Early onset dementia and marked involvement of frontal regions are features characterizing both NHD and other kinds of neurodegenerative disorders, such as Frontotemporal Lobar Degeneration (FTLD), and, in some cases, Alzheimer's...

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Source

Identifiers

PMID: 17088018
DOI: 10.1016/j.neulet.2006.10.029

Genes

TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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