Article
High rates of parasite recrudescence following intermittent preventive treatment with sulphadoxine-pyrimethamine during pregnancy in Benin.
Malaria journal - 10 Jun 2013
Moussiliou Azizath, De Tove Yolande Sissinto-Savi, Doritchamou Justin, Luty Adrian J F, Massougbodji Achille, Alifrangis Michael, Deloron Philippe, Ndam Nicaise Tuikue
Abstract excerpt
BACKGROUND: Despite widespread parasite resistance to sulphadoxine-pyrimethamine (SP) its use for intermittent preventative treatment during pregnancy remains the policy in Benin and throughout most of sub-Saharan Africa. METHODS: In a prospective study, 982 pregnant women were recruited in Benin and followed until delivery. The prevalence of point mutations in the pfdhfr and pfdhps genes associated with...
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