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Article

Molecular markers of resistance to sulphadoxine-pyrimethamine during intermittent preventive treatment of pregnant women in Benin.

Malaria journal - 19 Jul 2011

Bertin Gwladys, Briand Valérie, Bonaventure Diana, Carrieu Ambre, Massougbodji Achille, Cot Michel, Deloron Philippe

Abstract excerpt

BACKGROUND: The prevention of malaria faces with the repeated emergence of Plasmodium falciparum resistance to drugs, often involving point mutations of the target gene. In the pregnant woman, currently the WHO recommendation is the administration of an intermittent preventive treatment (IPTp) with sulphadoxine-pyrimethamine. Sulphadoxine-pyrimethamine (SP) resistance has increased for several years in Africa,...

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Benin
Chemoprevention
Dihydropteroate Synthase
Mefloquine
Pregnancy Complications

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PMID: 21767415
DOI: 10.1186/1475-2875-10-196
PMCID: PMC3199903

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Molecular markers of resistance to sulphadoxine-pyrimethamine during intermittent preventive treatment of pregnant women in Benin.PMID 21767415Read ↗

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