Article
Analysis of Genome-Wide Association Data.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
McRae Allan F
Abstract excerpt
The last decade has seen substantial advances in the understanding of the genetics of complex traits and disease. This has been largely driven by genome-wide association studies (GWAS), which have identified thousands of genetic loci associated with these traits and disease. This chapter provides a guide on how to perform GWAS on both binary (case-control) and quantitative traits. As poor data quality, through...
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