Article
Absence of activating killer immunoglobulin-like receptor genes combined with hepatitis C viral genotype is predictive of hepatocellular carcinoma.
Human immunology - 1 Oct 2013
Littera Roberto, Zamboni Fausto, Tondolo Vincenzo, Fantola Giovanni, Chessa Luchino, Orrù Nicola, Sanna Marco, Valentini Donatella, Cappai Luisella, Mulargia Marina, Caocci Giovanni, Arras Marcella, Floris Andrea, Orrù Sandro, La Nasa Giorgio, Carcassi Carlo
Abstract excerpt
Killer immunoglobulin-like receptors and their human leukocyte antigen class I ligands have a critical role in natural killer cell response to viral pathogens and tumors. To investigate whether killer immunoglobulin-like receptor genes could influence the chronic course of hepatitis C virus infection and/or progression to hepatocellular carcinoma we retrospectively analyzed a cohort of 228 patients transplanted...
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