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Article

Mechanisms that enhance sustainability of p53 pulses.

PloS one - 1 Jan 2013

Kim Jae Kyoung, Jackson Trachette L

Abstract excerpt

The tumor suppressor p53 protein shows various dynamic responses depending on the types and extent of cellular stresses. In particular, in response to DNA damage induced by γ-irradiation, cells generate a series of p53 pulses. Recent research has shown the importance of sustaining repeated p53 pulses for recovery from DNA damage. However, far too little attention has been paid to understanding how cells can...

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PMID: 23755198
DOI: 10.1371/journal.pone.0065242
PMCID: PMC3670918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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