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Article

Impact of natural genetic variation on gene expression dynamics.

PLoS genetics - 1 Jun 2013

Ackermann Marit, Sikora-Wohlfeld Weronika, Beyer Andreas

Abstract excerpt

DNA sequence variation causes changes in gene expression, which in turn has profound effects on cellular states. These variations affect tissue development and may ultimately lead to pathological phenotypes. A genetic locus containing a sequence variation that affects gene expression is called an "expression quantitative trait locus" (eQTL). Whereas the impact of cellular context on expression levels in general...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23754949
DOI: 10.1371/journal.pgen.1003514
PMCID: PMC3674999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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