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Lentivirus Replication and Regulation

1 Dec 1999

Abstract excerpt

Lentiviruses are associated with chronic diseases of the hematological and neurological systems in animals and man. In particular, human immunodeficiency virus type 1 (HIV-1) is the etiological agent of the global AIDS epidemic. The genomes of lentiviruses are complex, encoding a number of regulatory and accessory proteins not found in other retroviruses. This complexity is reflected in their replication cycle,...

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PMID: 10690406
DOI: 10.1146/annurev.genet.33.1.133

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