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Alcohol and HER2 polymorphisms as risk factor for cardiotoxicity in breast cancer treated with trastuzumab.

Anticancer research - 1 Jun 2013

Lemieux Julie, Diorio Caroline, Côté Marc-André, Provencher Louise, Barabé Frédéric, Jacob Simon, St-Pierre Christine, Demers Eric, Tremblay-Lemay Rosemarie, Nadeau-Larochelle Corinne, Michaud Annick, Laflamme Christian

Abstract excerpt

BACKGROUND: Trastuzumab has no major side-effects except the potential for cardiac toxicity. The main objective of this study was to evaluate the association between trastuzumab-associated cardiac toxicity and two potential risk factors: alcohol intake and HER2 polymorphisms. PATIENTS AND METHODS: In a retrospective cohort study of 237 women with non-metastatic HER2-positive breast cancer treated with...

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PMID: 23749910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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