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Article

Modeling human disease with pluripotent stem cells: from genome association to function.

Cell stem cell - 6 Jun 2013

Merkle Florian T, Eggan Kevin

Abstract excerpt

Mechanistic insights into human disease may enable the development of treatments that are effective in broad patient populations. The confluence of gene-editing technologies, induced pluripotent stem cells, and genome-wide association as well as DNA sequencing studies is enabling new approaches for illuminating the molecular basis of human disease. We discuss the opportunities and challenges of combining these...

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PMID: 23746975
DOI: 10.1016/j.stem.2013.05.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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