Article
New lessons learned from disease modeling with induced pluripotent stem cells.
Current opinion in genetics & development - 1 Oct 2012
Onder Tamer T, Daley George Q
Abstract excerpt
Cellular reprogramming and generation of induced pluripotent stem cells (iPSCs) from adult cell types have enabled the creation of patient-specific stem cells for use in disease modeling. To date, many iPSC lines have been generated from a variety of disorders, which have then been differentiated into disease-relevant cell types. When a disease-specific phenotype is detectable in such differentiated cells, the...
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