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Article

Analysis of copy number changes on chromosome 16q in male breast cancer by multiplex ligation-dependent probe amplification.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2013

Lacle Miangela M, Kornegoor Robert, Moelans Cathy B, Maes-Verschuur Anoek H, van der Pol Carmen, Witkamp Arjen J, van der Wall Elsken, Rueschoff Josef, Buerger Horst, van Diest Paul J

Abstract excerpt

Gene copy number changes have an important role in carcinogenesis and could serve as potential biomarkers for prognosis and targets for therapy. Copy number changes mapping to chromosome 16 have been reported to be the most frequent alteration observed in female breast cancer and a loss on 16q has been shown to be associated with low grade and better prognosis. In the present study, we aimed to characterize copy...

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PMID: 23743929
DOI: 10.1038/modpathol.2013.94

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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