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Article

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

12 May 2010

Abstract excerpt

BACKGROUND: Cancer genomes display characteristic patterns of chromosomal imbalances, often with diagnostic and prognostic relevance. Therefore assays for genome-wide copy number screening and simultaneous detection of copy number alterations in specific chromosomal regions are of increasing importance in the diagnostic work-up of tumors. RESULTS: We tested the performance of Multiplex Amplicon Quantification, a...

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Share to Genomic variations and chromosomal abnormalities
Share to Microtubule and mitosis dynamics
Share to Neuroblastoma Research and Treatments

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PMID: 20459859
DOI: 10.1186/1471-2164-11-298

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