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Article

New applications and developments in the use of multiplex ligation-dependent probe amplification.

Electrophoresis - 1 Dec 2008

Kozlowski Piotr, Jasinska Anna J, Kwiatkowski David J

Abstract excerpt

Multiplex ligation-dependent probe amplification (MLPA) is a commonly used technique for determining relative DNA sequence dosage (or copy number) in a complex DNA sample. Originally MLPA was designed as a copy number analysis tool for detecting disease-causing genomic mutations and has been successfully applied in the testing and identification of hundreds of genomic mutations in numerous genes including DMD,...

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Source

Identifiers

PMID: 19053154
DOI: 10.1002/elps.200800126

Genes

BRCA1
DMD
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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