Article
A Bayesian genome screening of maximum number of drinks as an alcoholism phenotype with the new Haseman-Elston method.
BMC genetics - 30 Dec 2005
Oh Cheongeun, Wang Shuang, Liu Nianjun, Chen Liang, Zhao Hongyu
Abstract excerpt
Common human disorders, such as alcoholism, may be the result of interactions of many genes as well as environmental risk factors. Therefore, it is important to incorporate gene x gene and gene x environment interactions in complex disease gene mapping. In this study, we applied a robust Bayesian genome screening method that can incorporate interaction effects to map genes underlying alcoholism through its...
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