Article
Reduced prevalence of cognitive impairment in families with exceptional longevity.
JAMA neurology - 1 Jul 2013
Cosentino Stephanie, Schupf Nicole, Christensen Kaare, Andersen Stacy L, Newman Anne, Mayeux Richard
Abstract excerpt
IMPORTANCE: Family studies of centenarians and long-lived persons have found substantial familial aggregation of survival to extreme ages; however, the extent to which such familial longevity is characterized by cognitively intact survival is not established. OBJECTIVE: To determine whether families with exceptional longevity are protected against cognitive impairment consistent with Alzheimer disease. DESIGN:...
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