Article
Role of familial factors in late-onset Alzheimer disease as a function of age.
Alzheimer disease and associated disorders - 1 Sept 1998
Wu Z, Kinslow C, Pettigrew K D, Rapoport S I, Schapiro M B
Abstract excerpt
Whereas early-onset Alzheimer disease (AD; usually onset at age < 50 years) has been defined with genetic mutation on chromosomes 1, 14, and 21, the degree of familial contribution to late-onset AD is unclear. Further, it is uncertain if subgroups of late-onset AD exist. To examine the influence of familial factors as a function of age in late-onset AD we investigated lifetime risks and age-specific hazard rates...
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