Article
Role of familial factors in late-onset Alzheimer disease as a function of age.
Alzheimer disease and associated disorders - 1 Sept 1998
Wu Z, Kinslow C, Pettigrew K D, Rapoport S I, Schapiro M B
Abstract excerpt
Whereas early-onset Alzheimer disease (AD; usually onset at age < 50 years) has been defined with genetic mutation on chromosomes 1, 14, and 21, the degree of familial contribution to late-onset AD is unclear. Further, it is uncertain if subgroups of late-onset AD exist. To examine the influence...
Topics
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 21
- DNA Mutational Analysis
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Phenotype
- Proportional Hazards Models
- Risk