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Article

Lipid-based signaling modulates DNA repair response and survival against Klebsiella pneumoniae infection in host cells and in mice.

American journal of respiratory cell and molecular biology - 1 Nov 2013

Huang Huang, Weaver Andrew, Wu Erxi, Li Yi, Gao Hongwei, Fan Weimin, Wu Min

Abstract excerpt

Klebsiella pneumoniae causes serious infections in the urinary tract, respiratory tract, and blood. Lipid rafts, also known as membrane microdomains, have been linked to the pathogenesis of bacterial infection. However, whether lipid rafts affect K. pneumoniae internalization into host cells remains unknown. Here, we show for the first time that K. pneumoniae was internalized into lung cells by activating lipid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23742126
DOI: 10.1165/rcmb.2013-0069OC
PMCID: PMC3931102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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