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Capsular polysaccharide enables Klebsiella pneumoniae to evade phagocytosis by blocking host-bacteria interactions

14 Feb 2025

Abstract excerpt

ABSTRACT Capsule polysaccharide (CPS) is among the most important virulence factors of Klebsiella pneumoniae . Previous studies demonstrated that CPS plays multiple functional roles, but the mechanism by which this virulence factor enhances the survival fitness of K. pneumoniae remains unclear. In this work, we demonstrate that CPS is the main cellular component that not only elicits the host immune response to...

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PMID: 39950808
DOI: 10.1128/mbio.03838-24

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