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Article

Variants in the promoter region of CYP7A1 are associated with neuromyelitis optica but not with multiple sclerosis in the Han Chinese population.

Neuroscience bulletin - 1 Oct 2013

Zhao Gui-Xian, Liu Ying, Li Zhen-Xin, Lv Chuan-Zhen, Traboulsee Anthony, Sadovnick A Dessa, Wu Zhi-Ying

Abstract excerpt

Multiple sclerosis (MS) and neuromyelitis optica (NMO) are common autoimmune demyelinating disorders of the central nervous system. The exact etiology of each remains unclear. CYP7A1 was reported to be associated with NMO in Korean patients, but this is yet to be confirmed in other populations. In this study, we used Sanger sequencing to detect SNPs in the promoter region of CYP7A1 in a population consisting of...

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Identifiers

PMID: 23740208
DOI: 10.1007/s12264-013-1347-6
PMCID: PMC5561957

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