Article
Common genetic variants in PRRC2A are associated with both neuromyelitis optica spectrum disorder and multiple sclerosis in Han Chinese population.
Journal of neurology - 1 Feb 2021
Zhang Juan, Chen Mei-Jiao, Zhao Gui-Xian, Li Hong-Fu, Wu Lei, Xu Yong-Feng, Liao Yajin, Yuan Zengqiang, Wu Zhi-Ying
Abstract excerpt
BACKGROUND: The proline-rich coiled-coil 2A (PRRC2A) gene has been reported to underlie risk of various autoimmune diseases. However, no data reveal the risk susceptibility of PRRC2A to neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) so far. OBJECTIVES: To explore the association between PRRC2A variants and NMOSD and MS susceptibility in Han Chinese population. METHODS: Totally, 207...
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