Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diagnostic value of the FHIT and p16 mRNA loss and the K-ras gene mutation in pleural fluids for malignant pleural effusion.

Cancer biomarkers : section A of Disease markers - 1 Jan 2013

Li Jian, Bao Qian-Lei, Wang Yi, Hu Yi-Ming, Chen Ping

Abstract excerpt

Inactivation of the tumor suppressor genes and activation of oncogenes are involved in the development of cancer. The aim of this study was to evaluate the diagnostic value of the fragile histidine triad (FHIT) and p16 mRNA loss and the K-ras gene mutation in distinguishing malignant from benign pleural effusion. A total of 50 patients with malignant pleural effusion and 30 patients with benign pleural effusion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Anhydride Hydrolases
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, p16

Share to Genes, ras

Share to Neoplasm Proteins

Share to Pleural Effusion, Malignant

Share to Polymorphism, Single-Stranded Conformational

Source

Open in PubMed Open full text

Identifiers

PMID: 23736021
DOI: 10.3233/CBM-130319
PMCID: PMC12928261

Genes

FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diagnostic value of the FHIT and p16 mRNA loss and the K-ras gene mutation in pleural fluids for malignant pleural effusion.PMID 23736021Read ↗

Diagnostic molecular biomarkers for malignant pleural effusions.Semantic proximity Read ↗

Aberrant DNA methylation profile in pleural fluid for differential diagnosis of malignant pleural mesotheliomaSemantic proximity Read ↗

[Alterations of FHIT gene and p16 gene in lung cancer and metastatic hilar lymph nodes].Semantic proximity Read ↗

Microsatellite alterations and cell-free DNA analysis: could they increase the cytology sensitivity in the diagnosis of malignant pleural effusion?Semantic proximity Read ↗

Clinical identification of malignant pleural effusionsSemantic proximity Read ↗

DNA Methylation Analysis of the SHOX2 and RASSF1A Panel Using Cell-Free DNA in the Diagnosis of Malignant Pleural EffusionSemantic proximity Read ↗

Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case–control study for risk assessmentSemantic proximity Read ↗

Combined Methylation of SHOX2 and RASSF1A Genes in Diagnosing Malignant Pleural EffusionSemantic proximity Read ↗

Mutation analysis of the FHIT gene in bronchoscopic specimens from patients with suspected lung cancer.Semantic proximity Read ↗

Diagnostic and Prognostic Value of SHOX2 and SEPT9 DNA Methylation and Cytology in Benign, Paramalignant and Malignant Pleural EffusionsSemantic proximity Read ↗

Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas.Semantic proximity Read ↗

Genetic Deletions in Sputum as Diagnostic Markers for Early Detection of Stage I Non–Small Cell Lung CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.