Article
Microsatellite alterations and cell-free DNA analysis: could they increase the cytology sensitivity in the diagnosis of malignant pleural effusion?
Rejuvenation research - 1 Jun 2012
Carpagnano Giovanna E, Costantino Elio, Palladino Grazia P, Lacedonia Donato, Martinelli Domenico, Orlando Silvio, Foschino-Barbaro Maria P
Abstract excerpt
BACKGROUND: The exact diagnosis of malignant pleural effusions (PE) is difficult and often requires combined procedures, because the cytological examination of pleural fluid does not detect tumoral cells in 40% of malignant effusion cases. The aim of this study was to analyze microsatellite alterations (MA) in malignant PE and to determine their diagnostic value as an additional test to cytological examination....
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