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Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case–control study for risk assessment

31 Oct 2007

Abstract excerpt

The purpose of this study was to define a biomarker panel for detection of cancer cells in cytologically negative sputum and to evaluate the panel for assessment of lung cancer risk. We examined 19 genetic and epigenetic markers using a sensitive fluorescence-based method in cytologically negative sputum and in lung tumour tissues from 82 lung cancer patients. We also used these markers to test the sputum of 37...

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Share to Epigenetics and DNA Methylation
Share to Lung Cancer Treatments and Mutations
Share to RNA modifications and cancer

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PMID: 17973238
DOI: 10.1002/path.2246

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