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Article

Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies.

Hepatology (Baltimore, Md.) - 1 Nov 2013

Pedersen Jannie, Carlsen Thomas H R, Prentoe Jannick, Ramirez Santseharay, Jensen Tanja B, Forns Xavier, Alter Harvey, Foung Steven K H, Law Mansun, Gottwein Judith, Weis Nina, Bukh Jens

Abstract excerpt

UNLABELLED: Immunotherapy and vaccine development for hepatitis C virus (HCV) will depend on broadly reactive neutralizing antibodies (NAbs). However, studies in infectious strain JFH1-based culture systems expressing patient-derived Core-NS2 proteins have suggested neutralization resistance for specific HCV strains, in particular, of genotype 2. To further examine this phenomenon, we developed a panel of HCV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23729237
DOI: 10.1002/hep.26524
PMCID: PMC4415732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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