Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mouse model of adult-onset anaemia due to erythropoietin deficiency.

Nature communications - 1 Jan 2013

Yamazaki Shun, Souma Tomokazu, Hirano Ikuo, Pan Xiaoqing, Minegishi Naoko, Suzuki Norio, Yamamoto Masayuki

Abstract excerpt

Erythropoietin regulates erythropoiesis in a hypoxia-inducible manner. Here we generate inherited super-anaemic mice (ISAM) as a mouse model of adult-onset anaemia caused by erythropoietin deficiency. ISAM express erythropoietin in the liver but lack erythropoietin production in the kidney. Around weaning age, when the major erythropoietin-producing organ switches from the liver to the kidney, ISAM develop...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia
Share to Bone Marrow
Share to Embryo Loss

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythroblasts

Share to Erythropoietin

Share to Hematopoiesis

Share to Integrases

Share to Staining and Labeling

Source

Identifiers

PMID: 23727690
DOI: 10.1038/ncomms2950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mouse model of adult-onset anaemia due to erythropoietin deficiency.PMID 23727690Read ↗

A mouse model for an erythropoietin-deficiency anemia.Semantic proximity Read ↗

Zebrafish erythropoiesis and the utility of fish as models of anemiaSemantic proximity Read ↗

Erythropoiesis: Model systems, molecular regulators, and developmental programsSemantic proximity Read ↗

Advances in understanding the mechanisms of erythropoiesis in homeostasis and diseaseSemantic proximity Read ↗

Using the Zebrafish as a Genetic Model to Study ErythropoiesisSemantic proximity Read ↗

Human and murine erythropoiesisSemantic proximity Read ↗

Advances in understanding erythropoiesis: evolving perspectivesSemantic proximity Read ↗

Developmentally-faithful and effective human erythropoiesis in immunodeficient and Kit mutant mice.Semantic proximity Read ↗

Developmental biology of erythropoiesisSemantic proximity Read ↗

Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.Semantic proximity Read ↗

The human erythropoietin receptor gene rescues erythropoiesis and developmental defects in the erythropoietin receptor null mouseSemantic proximity Read ↗

EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.