A group-specific sequencing approach to investigate the presence of atypical human leucocyte antigen alleles.

doi:10.1111/iji.12070

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Article

A group-specific sequencing approach to investigate the presence of atypical human leucocyte antigen alleles.

International journal of immunogenetics - 1 Dec 2013

Foster L, Tate D, Poulton K

Abstract excerpt

Accurate human leucocyte antigen (HLA) typing results are essential in determining the degree of compatibility between donor and recipient in both solid organ (SO) and hematopoietic stem cell (HSC) transplantation. Current HLA typing methodologies can generate ambiguous results which may need resolving. This group-specific sequencing approach allowed investigation into the presence of the low expressor...

Topics

Alleles
Base Sequence
DNA Primers
Exons
Genotype
HLA Antigens
HLA-A24 Antigen
HLA-DQ beta-Chains
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Organ Transplantation

Polymerase Chain Reaction

Polymorphism, Genetic

Reproducibility of Results

Sequence Analysis, DNA

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 23724946
DOI: 10.1111/iji.12070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23724946-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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