Article
A national proficiency scheme for human leucocyte antigen typing by next-generation sequencing.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2022
Lin Guigao, Zhang Kuo, Li Jinming
Abstract excerpt
BACKGROUND: Accurate human leucocyte antigen (HLA) typing is essential for solid organ transplantation (SOT) and hematopoietic stem cell transplantation (HSCT). Next-generation sequencing (NGS) is increasingly adopted by clinical laboratories performing HLA typing. To ensure reliable NGS-based HLA typing throughout China, a HLA-NGS proficiency testing (PT) scheme was set up. METHODS: A panel of 10 DNA reference...
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