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Article

Lipopolysaccharide-induced M2 to M1 macrophage transformation for IL-12p70 production is blocked by Candida albicans mediated up-regulation of EBI3 expression.

PloS one - 1 Jan 2013

Zheng Xing-Feng, Hong Yu-Xiao, Feng Gui-Jie, Zhang Gao-Feng, Rogers Helen, Lewis Michael A O, Williams David W, Xia Zhao-Fan, Song Bing, Wei Xiao-Qing

Abstract excerpt

Macrophages are heterogeneous cell populations that are present in all tissues. Macrophages can be divided into classically activated inflammatory macrophages (M1) and alternatively activated anti-inflammatory macrophages (M2). It has been generally accepted that M1 macrophages are polarised in an inflammatory environment to produce pro-inflammatory cytokines, whilst M2 macrophages are involved in...

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Identifiers

PMID: 23724011
DOI: 10.1371/journal.pone.0063967
PMCID: PMC3664618

Genes

EBI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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