Article
Factors determining the formation and release of bioactive IL-12: regulatory mechanisms for IL-12p70 synthesis and inhibition.
Biochemical and biophysical research communications - 8 Aug 2008
Zhang Sheng, Wang Qin
Abstract excerpt
IL-12 is an important type 1 immune activation cytokine. It is known that macrophages and dendritic cells the major cell types producing this cytokine and that these cells may release both the biologically inactive form (IL-12p40) and active form (IL-12p70) of IL-12. In this review, the latest in...
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