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Article

EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway

5 Dec 2024

Abstract excerpt

Candida albicans is a fungal pathobiont colonizing mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C. albicans invades mucosal tissues activating EGFR-MAPK signalling pathways in epithelial cells via the action of its peptide toxin candidalysin. However, our knowledge of the epithelial mechanisms involved during C. albicans colonization is rudimentary. Here,...

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PMID: 39635778
DOI: 10.1080/21505594.2024.2435374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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