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Article

Integrated analysis of recurrent properties of cancer genes to identify novel drivers.

Genome biology - 29 May 2013

D'Antonio Matteo, Ciccarelli Francesca D

Abstract excerpt

The heterogeneity of cancer genomes in terms of acquired mutations complicates the identification of genes whose modification may exert a driver role in tumorigenesis. In this study, we present a novel method that integrates expression profiles, mutation effects, and systemic properties of mutated genes to identify novel cancer drivers. We applied our method to ovarian cancer samples and were able to identify...

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Share to Gene Expression Regulation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23718799
DOI: 10.1186/gb-2013-14-5-r52
PMCID: PMC4054099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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