Article
Deletion analysis of Streptococcus pneumoniae late competence genes distinguishes virulence determinants that are dependent or independent of competence induction.
Molecular microbiology - 1 Jul 2015
Zhu Luchang, Lin Jingjun, Kuang Zhizhou, Vidal Jorge E, Lau Gee W
Abstract excerpt
The competence regulon of Streptococcus pneumoniae (pneumococcus) is crucial for genetic transformation. During competence development, the alternative sigma factor ComX is activated, which in turn, initiates transcription of 80 'late' competence genes. Interestingly, only 16 late genes are essen...
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