Article
Fine‐tuning cellular levels of DprA ensures transformant fitness in the human pathogen Streptococcus pneumoniae
11 Jul 2018
Abstract excerpt
Natural genetic transformation is a widespread mechanism of horizontal gene transfer. It involves the internalization of exogenous DNA as single strands and chromosomal integration via homologous recombination, promoting acquisition of new genetic traits. Transformation occurs during a distinct physiological state called competence. In Streptococcus pneumoniae, competence is controlled by ComDE, a two-component...
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