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Article

ClpC acts as a negative regulator of competence in Streptococcus thermophilus.

Microbiology (Reading, England) - 1 Jun 2011

Biørnstad Truls Johan, Håvarstein Leiv Sigve

Abstract excerpt

The alternative sigma factor ComX is a key regulator of natural transformation in members of the genus Streptococcus. ComX controls expression of the late competence genes, which are essential for DNA binding, uptake and recombination. In Streptococcus pneumoniae, it has been demonstrated that ComX is degraded by ClpEP at the end of the competence period. In the present study we show that a different Clp protease...

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PMID: 21436217
DOI: 10.1099/mic.0.046425-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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