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Article

Medullospheres from DAOY, UW228 and ONS-76 cells: increased stem cell population and proteomic modifications.

PloS one - 1 Jan 2013

Zanini Cristina, Ercole Elisabetta, Mandili Giorgia, Salaroli Roberta, Poli Alice, Renna Cristiano, Papa Valentina, Cenacchi Giovanna, Forni Marco

Abstract excerpt

BACKGROUND: Medulloblastoma (MB) is an aggressive pediatric tumor of the Central Nervous System (CNS) usually treated according to a refined risk stratification. The study of cancer stem cells (CSC) in MB is a promising approach aimed at finding new treatment strategies. METHODOLOGY/PRINCIPAL FINDINGS: The CSC compartment was studied in three characterized MB cell lines (DAOY, UW228 and ONS-76) grown in standard...

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Identifiers

PMID: 23717474
DOI: 10.1371/journal.pone.0063748
PMCID: PMC3663798

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