Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucose homeostasis in mice is transglutaminase 2 independent.

PloS one - 1 Jan 2013

Iismaa Siiri E, Aplin Mark, Holman Sara, Yiu Ting W, Jackson Kristy, Burchfield James G, Mitchell Christopher J, O'Reilly Liam, Davenport Aimee, Cantley James, Schmitz-Peiffer Carsten, Biden Trevor J, Cooney Gregory J, Graham Robert M

Abstract excerpt

Transglutaminase type 2 (TG2) has been reported to be a candidate gene for maturity onset diabetes of the young (MODY) because three different mutations that impair TG2 transamidase activity have been found in 3 families with MODY. TG2 null (TG2(-/-)) mice have been reported to be glucose intoler...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Diabetes Mellitus
Share to Glucose Tolerance Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to Insulin-Secreting Cells

Share to Islets of Langerhans

Share to Protein Glutamine gamma Glutamyltransferase 2

Share to Transglutaminases

Source

Open in PubMed Open full text

Identifiers

PMID: 23717413
DOI: 10.1371/journal.pone.0063346
PMCID: PMC3661676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23717413-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucose homeostasis in mice is transglutaminase 2 independent.PMID 23717413Read ↗

Missense mutations in theTGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetesSemantic proximity Read ↗

Functional characterization of naturally occurring transglutaminase 2 mutants implicated in early-onset type 2 diabetes.Semantic proximity Read ↗

Phenotypic characterization of polygenic type 2 diabetes in TALLYHO/JngJ mice.Semantic proximity Read ↗

Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype.Semantic proximity Read ↗

G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting.Semantic proximity Read ↗

Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models.Semantic proximity Read ↗

Mouse Models with SGLT2 Mutations: Toward Understanding the Role of SGLT2 beyond Glucose Reabsorption.Semantic proximity Read ↗

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes.Semantic proximity Read ↗

Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene.Semantic proximity Read ↗

Obesity-induced diabetes in mouse strains treated with gold thioglucose: a novel animal model for studying β-cell dysfunction.Semantic proximity Read ↗

Tissue-specific responses to loss of transglutaminase 2.Semantic proximity Read ↗

Characterization of TG2 and TG1-TG2 double knock-out mouse epidermis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.