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APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry.

Carcinogenesis - 1 Oct 2013

Xuan Dennis, Li Guoliang, Cai Qiuyin, Deming-Halverson Sandra, Shrubsole Martha J, Shu Xiao-Ou, Kelley Mark C, Zheng Wei, Long Jirong

Abstract excerpt

Copy number variations occur frequently in the genome and are a significant source of human genetic variation accounting for disease. Recently, we discovered a common deletion located in the APOBEC3A and APOBEC3B genes significantly associated with breast cancer in Chinese women. Investigating this locus in other populations would be an expedient way to evaluate the generalizability of the novel finding. We...

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Identifiers

PMID: 23715497
DOI: 10.1093/carcin/bgt185
PMCID: PMC3786378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry.PMID 23715497Read ↗

APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.Semantic proximity Read ↗

A common deletion in the APOBEC3 genes and breast cancer risk.Semantic proximity Read ↗

APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.Semantic proximity Read ↗

APOBEC3A/B deletion polymorphism and endometrial cancer risk.Semantic proximity Read ↗

Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation.Semantic proximity Read ↗

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer.Semantic proximity Read ↗

Germline APOBEC3B deletion increases somatic hypermutation in Asian breast cancer that is associated with Her2 subtype, PIK3CA mutations and immune activationSemantic proximity Read ↗

Rare Copy Number Variants (CNVs) and Breast Cancer RiskSemantic proximity Read ↗

APOBEC3A/B deletion polymorphism and cancer risk.Semantic proximity Read ↗

Germline <i>APOBEC3B</i> deletion in Asian women increases somatic hypermutation in breast cancer that is associated with Her2 subtype, <i>PIK3CA</i> mutations, immune activation, and increased survivalSemantic proximity Read ↗

The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European populationSemantic proximity Read ↗

Population stratification of a common APOBEC gene deletion polymorphism.Semantic proximity Read ↗

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