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Article

Population stratification of a common APOBEC gene deletion polymorphism.

PLoS genetics - 20 Apr 2007

Kidd Jeffrey M, Newman Tera L, Tuzun Eray, Kaul Rajinder, Eichler Evan E

Abstract excerpt

The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a detailed sequence and population genetic analysis of a 29.5-kb common human deletion polymorphism that removes the APOBEC3B gene. We developed a PCR-based genotyping assay, characterized 1,277 human diversity samples, and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 17447845
DOI: 10.1371/journal.pgen.0030063
PMCID: PMC1853121

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Population stratification of a common APOBEC gene deletion polymorphism.PMID 17447845Read ↗

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A high-resolution survey of deletion polymorphism in the human genome.Semantic proximity Read ↗

Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans.Semantic proximity Read ↗

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