Article
A neu view of invasive lobular breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2013
Bose Ron
Abstract excerpt
Genome sequencing of relapsed, invasive lobular breast cancer identified actionable mutations in 86% of the cases. HER2 alterations occur in 27% of the cases, including 4 cases with activating HER2 mutations and 1 with a novel HER2-GRB7 gene fusion. This fusion links the HER2 tyrosine kinase doma...
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