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Article

Twisted Tapestry of Tumors: Updates in Molecular Pathology of Breast Tumors.

Surgical pathology clinics - 1 Jun 2026

Hoda Raza S, Wen Hannah Y

Abstract excerpt

This article explores the expanding role of molecular diagnostics in breast pathology. It emphasizes how immunohistochemistry, fluorescence in situ hybridization, and next-generation sequencing define tumor subtypes with recurrent genetic alterations, while predictive biomarkers such as ESR1, human epidermal growth factor receptor 2, PD-L1, and BRCA1/2 direct targeted therapies. The article highlights the...

Read the complete abstract on PubMed

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Share to Biomarkers, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 42091275
DOI: 10.1016/j.path.2026.01.005

Genes

BRCA1
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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