Article
Association between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer's disease in two independent European samples.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2013
Porcelli Stefano, Salfi Raffaele, Politis Antonis, Atti Anna Rita, Albani Diego, Chierchia Armando, Polito Letizia, Zisaki Aikaterini, Piperi Christina, Liappas Ioannis, Alberti Siegfried, Balestri Martina, Marsano Agnese, Stamouli Evangelia, Mailis Antonis, Biella Gloria, Forloni Gianluigi, Bernabei Virginia, Ferrari Barbara, Lia Loredana, Papadimitriou George N, De Ronchi Diana, Serretti Alessandro
Abstract excerpt
Among the several genes associated with late-onset Alzheimer's disease (LOAD), recently, Sirtuin genes have roused a growing interest because of their involvement in metabolic homeostasis and in brain aging. Particularly SIRT2 gene has been associated with Alzheimer's disease (AD) as well as with mood disorders. The aim of this study is to investigate the possible associations between Sirtuin 2 gene (SIRT2)...
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